Search on: ACETOLACTATE SYNTHETASE 
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Descriptor English:   Acetolactate Synthase 
Descriptor Spanish:   Acetolactato Sintasa 
Descriptor Portuguese:   Acetolactato Sintase 
Synonyms English:   Acetohydroxyacid Synthetase I
Acetoxyhydroxyacid Synthase III
Acid Synthase, Acetohydroxy
Acid Synthetase, Acetohydroxy
Synthase III, Acetoxyhydroxyacid
Synthase, Acetohydroxy Acid
Synthase, Acetolactate
Synthetase I, Acetohydroxyacid
Synthetase, Acetohydroxy Acid
Synthetase, Acetolactate
Acetohydroxy Acid Synthetase
Acetohydroxy Acid Synthase
Acetolactate Synthetase  
Tree Number:   D08.811.913.200.324
D12.776.331.049
Definition English:   A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the biosynthesis of VALINE and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of ISOLEUCINE. This enzyme was formerly listed as EC 4.1.3.18. 
History Note English:   91(75); was see under KETOACID-LYASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   100 
Unique Identifier:   D000095 

Occurrence in VHL: 		 

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